Risk Factors For Prostate Cancer

Genetic studies conducted have found out that HOXB13 and BRCA genes increase the risk of prostate cancer. Mutation of the BRCA1 gene multiples the risk of prostate cancer twofold. On the other hand, mutation of the BRCA2 ...

Established and defined risk factors for prostate cancer are age, family history and race. Age is the greatest risk factor known for prostate cancer. The prevalence of prostate cancer rises with increasing age.

prostate cancer risk 2

There are numerous studies and evidence suggesting that prostate cancer is also familial and hereditary. Studies show increased risk of developing prostate cancer depending on the number of family members with prostate cancer, degree of relationship with such members and if such family members developed the disease early. For example, history of prostate cancer in the father multiplies the normal risk twofold for a person whereas the prostate cancer in a brother multiplies the risk threefold. If both the father and a brother have a history of prostate cancer in the same family, the risk is multiplied fivefold.

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Genetic studies conducted have found out that HOXB13 and BRCA genes increase the risk of prostate cancer. Mutation of the BRCA1 gene multiples the risk of prostate cancer twofold. On the other hand, mutation of the BRCA2 gene may increase the risk of early onset of the prostate cancer, high gleason score, and malignant progression of the disease by five to seven times.

According to the studies carried out, men of African American and Jamaican descent in the United States have the highest rate of prostate cancer in the world. Men of Asian descent have lower rates of the disease. However, Asian Americans have higher rate of the disease than their ascendants in Asia, and Japanese descendants in the United States have higher rate of prostate cancer than their ascendants in Japan, as well.

Prostate Cancer

Prostate Cancer

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Cantact Dr. Fatih Atug

Fatih Atug, M.D.
Urologist and Robotic Surgery Specialist

+90 212 234 5958

+90 532 234 5504

[email protected]

  Harbiye Mahallesi, Maçka Caddesi,
Bahriye Apt. No:13 D: 3
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